00596nz a2200217n 4500 211208|||anznnbab||||||||||||||a|||||||d homoit0000001 https://homosaurus.org/v3/homoit0000001 homoit 5-alpha reductase deficiency 5-ARD Intersex variations https://homosaurus.org/v3/homoit0000669 People with 5-alpha reductase deficiency, abbreviated as 5-ARD, have XY chromosomes, testes, and typical levels of testosterone, but their bodies do not have the enzyme responsible for converting testosterone to the more powerful androgen dihydrotestosterone (DHT). This affects how an individual's external sex characteristics develop, and people born with 5-ARD often have genital differences that are noticed at birth. In adolescence, people with 5-ARD typically develop some features associated with testosterone puberty, and they may experience genital growth at this point.